Synapse-Specific Gene Expression: Role in Synaptic Plasticity and Memory Storage?
Memory storage is thought to be mediated by changes in the structure and/or molecular composition of synapses. This process requires the expression of particular gene products, but how proteins are targeted to synapses undergoing modification still remains a mystery. Here, Steward will describe a cellular mechanism through which particular mRNAs are targeted to synaptic sites on dendrites, where they are locally translated.
Department of Anatomy and Neurobiology, University of California, Irvine